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Titlebook: Antiviral Drug Discovery and Development; Xinyong Liu,Peng Zhan,Vasanthanathan Poongavanam Book 2021 The Editor(s) (if applicable) and The

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https://doi.org/10.1007/978-3-030-80538-8has increased the cure rates to nearly 100%. DAA therapy is among the best examples of success in the fight against viral infections. DAAs have transformed HCV management and have opened the door for the global eradication of HCV.
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Moving Fast Toward Hepatitis B Virus Elimination,-HBV drug development strategies. Many of them are already in clinical trial phase 1 or 2, while others with promising results are still in preclinical stages. As research intensifies, potential HBV curative therapies and modalities in the pipeline are now on the horizon.
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Discovery and Development of Antiviral Therapies for Chronic Hepatitis C Virus Infection,has increased the cure rates to nearly 100%. DAA therapy is among the best examples of success in the fight against viral infections. DAAs have transformed HCV management and have opened the door for the global eradication of HCV.
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Exploiting Ubiquitin Ligases for Induced Target Degradation as an Antiviral Strategy,the UPS to degrade antiviral cellular host factors. Finally, I describe how we can exploit the same proteolytic machinery to enable PROTACs (Proteolysis-Targeting Chimeras) to degrade essential viral proteins. Successful implementation of this modality will add to the arsenal of emerging antiviral t
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An Update on Antiretroviral Therapy,uture prospects towards reducing pill burden and developing long-acting drugs and novel antiretroviral therapies. In addition, we summarize efforts to cure HIV, including pharmaceutical strategies focused on the elimination of the virus.
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