Titlebook: Antiepileptic Drugs; Pharmacology and The Mervyn J. Eadie,Frank J. E. Vajda Book 1999 Springer-Verlag Berlin Heidelberg 1999 catecholamines

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Carbamazepine, of action at the molecular level was unclear. The latter has now been elucidated, and considerable additional information has become available concerning the disposition, interactions and toxicity of the drug, mainly in humans, whilst its range of therapeutic uses has expanded. The present chapter deals chiefly with this newer information.

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Gabapentin,ic profile, minimal propensity for drug interactions, and lack of demonstrable or reported idiosyncratic reactions to date, the drug may have advantages in the treatment of epilepsy, when used as add-on therapy.

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Book 1999volume the then available data on the topic of antiepileptic drugs were col­ lated and analysed. Over the intervening years knowledge in this area has grown progressively. More new antiepileptic drugs than the total number of agents that were in common use 15 years ago have in the interval either co

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Epileptogenesis: Electrophysiology,referenced herein do point to the larger literature. Expectably, many of the essentials arise from experimental work in animals, but the ideas are usually supported by some specific studies in humans.

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Eisenwerkstoffe und ihre Anwendung,enyltriazine compounds, which had weak antifolate properties, proved to be potent anticonvulsants. Lamotrigine was developed from these compounds, though neither short-term nor chronic lamotrigine therapy appears to be associated with significant changes in serum or red cell folate concentrations (. and . 1992).

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Cellular Actions of Antiepileptic Drugs, 1994 the manufacturer and the United States Federal Drug Administration recommended that, if clinically possible, patients be withdrawn from felbamate. Fortunately, the remaining newly developed antiepileptic drugs have been approved in many countries and are currently in use.