Titlebook: Antiepileptic Drug Discovery; Novel Approaches Alan Talevi,Luisa Rocha Book 2016 Springer Science+Business Media New York 2016 Antiepilepto

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,Massive Decken zwischen I-Trägern,ids can regulate the expression of epileptic seizures as well as the epileptogenesis process. Some of them suggest that cannabinoids may represent a therapeutic approach for different types of epilepsy. However, experimental evidence indicates that the effects of cannabinoids depend on several exper

covert

https://doi.org/10.1007/978-3-662-25897-2ted that glutamate plays an important role in seizure generation and spread. Glutamate is the predominant excitatory neurotransmitter in the brain, exerting its action through ionotropic and metabotropic receptors. Notably, a significant increase of extracellular glutamate release was observed in hi

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,Angaben für die Berechnung von Trägern,tability. Neurosteroids suppress seizures, and this action is particularly important in women with epilepsy, who may experience seizure exacerbation due to hormonal fluctuations associated with their menstrual cycle, called catamenial epilepsy. Neurosteroids exert their anticonvulsant action by incr

incredulity

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https://doi.org/10.1007/978-3-662-12947-0lepsy. These are the ketogenic diet, medium-chain triglyceride regime, modified Atkins diet and low glycemic index treatment, all of which have been used clinically. These nutritional procedures are effective and have few adverse collateral actions. A related diet is caloric restriction, which can b

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https://doi.org/10.1007/978-3-662-12947-0e genetic engineering of viruses or plasmids and subsequent transfection into cells that will express transgenes in the central nervous system (CNS) may allow specific treatment in epileptogenic foci while sparing healthy brain tissue, and minimize the side effects of antiepileptic drug treatment. P

施加

https://doi.org/10.1007/978-3-7091-9787-5itro. We describe three approaches that represent an excellent opportunity for the study of the underlying mechanisms of pharmacoresistant epilepsy: in vitro electrophysiological recordings, in vitro procedures for receptor evaluation, and genomic analyses. These procedures could allow individual di

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