Titlebook: Antiemetics in the Supportive Care of Cancer Patients; Maurizio Tonato Conference proceedings 1996 Springer-Verlag Berlin Heidelberg 1996

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https://doi.org/10.1007/978-3-322-89386-4Nausea and vomiting are common and familiar side-effects of opioid drugs, but surprisingly few data on the incidence and characteristics of this phenomenon in cancer patients can be found in the literature. In the few studies available the percentage of patients suffering opi-oid-related emesis varied from 2.7% [1] to 40% [2].

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Antiemetic Therapy in Cancer Patients Submitted to Narcotic Analgesics,Nausea and vomiting are common and familiar side-effects of opioid drugs, but surprisingly few data on the incidence and characteristics of this phenomenon in cancer patients can be found in the literature. In the few studies available the percentage of patients suffering opi-oid-related emesis varied from 2.7% [1] to 40% [2].

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Unsolved Problems and Future Prospects,Although in the last few years the control of chemotherapy-induced nausea and vomiting has received increasing attention and new antiemetic drugs have been made available, the control of these symptoms is still far from being completely satisfactory.

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Methodology of Antiemetic Trials,and tolerability of therapies in cancer patients receiving chemotherapy. This is necessary not only to obtain optimal control of systematic errors, but also to describe their influence on the statistical analysis of the responses.

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Antiemetic Therapy in Paediatric Patients,he result of, in the main, more intensive chemotherapy and radiotherapy regimens which have been associated with increased toxicity, in particular acute side-effects due to myelosuppression, alopecia and nausea and vomiting.

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Admonish

Einzelkosten- und Deckungsbeitragsrechnungriety of other conditions that one should always consider before beginning antiemetic treatment. Nausea and vomiting affect very negatively the psychological status, nutritional balance, social relationships, and ultimately, quality of life of the patient. Furthermore, when nausea and vomiting are c

Manifest

Einzelkosten- und Deckungsbeitragsrechnungoth have a variety of deleterious effects on the patient’s quality of life during treatment. Vomiting itself places a considerable physical stress on the body in patients who may already be weakened by their disease and any concomitant surgery. Tearing of the oesophagus (Mallory-Weiss Syndrome) and

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Einzelkosten- und Deckungsbeitragsrechnungy. Elucidation of the mechanism of action of various antiemetic agents has led to a better understanding of the physiology upon which the emetic reflex arc is based and this in turn has led to the development of more selective agents with greater efficacy and an improved efficacy/toxicity ratio. How