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Titlebook: Antidepressants; From Biogenic Amines Matthew Macaluso,Sheldon H. Preskorn Book 2019 Springer Nature Switzerland AG 2019 Mood disorders.Tre

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Selective Serotonin Reuptake Inhibitors, but differ in terms of pharmacokinetics and effects on CYP450 enzymes, which is detailed in this chapter. Further information will be provided regarding safety, clinical indications/uses, and dosing recommendations.
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Clinical Implications of the STAR*D Trial,study and selected ancillary studies appended to the primary trial. The chapter describes the participants, their recruitment and treatment, and the study design, primary outcomes, and clinically informative results. In particular, the chapter describes acute phase response and remission rates from
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Serotonin and Norepinephrine Reuptake Inhibitors,e 5-HT and NE transporters with varying levels of potency and binding affinity ratios. Unlike the selective serotonin (5-HT) reuptake inhibitors (SSRIs), most of these antidepressants have an ascending rather than a flat dose–response curve. The chapter provides a brief review of the chemistry, phar
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Neurostimulation Therapies,of adequate trials of medication and psychotherapy. Neuromodulation treatments offer a qualitatively different modality of treatment that can frequently prove efficacious in these treatment-refractory patients. The field of neuromodulation focuses on the use of electrical/electromagnetic energy, bot
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Current Role of Herbal and Natural Preparations,not responded to and/or had adverse effects from standard therapies, herbal and natural medications represent a potentially valuable alternative. This chapter will review several natural remedies used in the treatment of depression. Specific remedies covered include St. John’s wort (SJW), S-adenosyl
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