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Titlebook: Antibody Phage Display; Methods and Protocol Philippa M. O’Brien,Robert Aitken Book 20021st edition Humana Press 2002

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,Der stationäre elektrische Strom,ers to virtually any antigen (.) (.). However, it is unlikely that the heavy (.) and light (.) chains of the Abs obtained from these libraries resemble original in vivo pairings. In certain autoimmune diseases and immunological processes, such as B-cell tolerance, these V. and V. combinations can be
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,Allgemeine Vorgänge in linearen Systemen,he libraries that have been produced vary considerably, from small libraries of 10. up to large libraries>10.. Often an Ab with the desired specificity exists at low frequencies in the recombinant Ab repertoire. It is therefore necessary to have an effective technique for the enrichment and identifi
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Systeme mit nichtlinearen Elementen,g., Petri dishes, microtiter plate wells, and immunotubes). This straightforward method is easy to perform and has been shown to be successful for a diverse set of Ags (for review, ..). However, phage Ab selections on some proteins and especially on peptides are not always successful, which is often
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https://doi.org/10.1007/978-3-662-25911-5al antibodies (MAbs) against a plethora of viral antigens (Ag) (.-.). However, sometimes the isolation of a given Ab can be particularly difficult because of the predominance of some epitopes, and, in the case of impure Ags, because the protein or compound of interest is present in a low amount. Man
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,Ausgleichsvorgänge in linearen Systemen,al antibodies (MAbs) with desired specificity (.,.). However, following selection of such libraries, certain epitope specificities may dominate the cloned Abs because, for example, the epitope is immunodominant or because Abs to that epitope have a selective advantage in the panning process arising
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https://doi.org/10.1007/978-3-662-25912-2 as bone marrow, lymph node, or peripheral blood lymphocytes from patients with various diseases, or from healthy individuals (.,.). Many human MAb Fabs or scFvs specific for viral pathogens, self antigens (Ags), or nonself Ags have been isolated by phage display system. This technology is expected
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