Titlebook: Antibody Glycosylation; Marija Pezer Book 2021 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature

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Die astronomischen Instrumente, indications. Full-length IgG mAbs are large proteins that are subject to multiple posttranslational modifications (PTMs) during biosynthesis, purification, or storage, resulting in micro-heterogeneity. The production of recombinant mAbs in nonhuman cell lines may result in loss of structural fideli

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https://doi.org/10.1007/978-3-662-59054-6iated with different diseases and show a promising biomarker potential for diagnosis and prognosis of disease advancement. On the other hand, therapeutic biomolecules based on structural and functional features of Igs demand stringent quality control during the production process to ensure their saf

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Einführung in die symbolische Logik used in high-throughput settings, especially for the glycomic characterization of IgG. A collection of these tools, and the databases they rely on, are presented in this chapter. Specific applications are detailed in examples of immunoglobulin glycomics and glycoproteomics data processing workflows

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