Titlebook: Antibody Expression and Production; Mohamed Al-Rubeai Book 2011 Springer Science+Business Media B.V. 2011 Antibody.Biopharmaceuticals.Cell

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Book 2011ficantly. The importance of antibody applications is reflected in their increasing clinical and industrial applications as well as in the progression of established and emerging production strategies. This volume provides detailed coverage of the generation, optimization, characterization, productio

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1389-6946 ransgenic animal and plants.Scientific and technical approacEngineered antibodies currently represent over 30% of biopharmaceuticals in clinical trials and their total worldwide sales continue to increase significantly. The importance of antibody applications is reflected in their increasing clinica

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Expression of Antibody in Mammalian Cells,aceuticals, many of which are antibodies. Historically, mammalian cells were mainly chosen for whole IgG manufacturing because of product quality requirements like e.g. glycosylation, folding and assembly of the individual chains, which make microbial expression difficult. However, during the past 2

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