Titlebook: Antibodies; Structure, Synthesis Andor Szentivanyi (Dean of the College of Medicine Book 1987 Plenum Press, New York 1987 aging.antibody.au

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https://doi.org/10.1007/978-3-642-92196-4h the existence of a network of idiotypes (ids) and anti-ids. The elements in this network (B cells, T cells, and serum antibodies) normally exist in a steady state. Introduction of antigen results in expansion of specific clones thereby perturbing the steady state. Subsequent shifts in the distribu

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https://doi.org/10.1007/978-3-642-92196-4diotypic anti-idiotypic interactions in the regulation of the human immune response to antigen has been less extensively studied. In this review we will discuss data obtained from our laboratory 011 the role the idiotypic network plays in the regulation of human immunity in health and in disease sta

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https://doi.org/10.1007/978-3-642-92196-4ditionally defined as the body’s immune system turning against itself to produce lymphocytes reactive with self-components. These lymphocytes may be B cells secreting autoantibodies like those responsible for hemolytic anemia, T cells attacking and destroying target organs such as the thyroid, or mo

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https://doi.org/10.1007/978-3-642-92196-4rial toxins, such as those causing tetanus and diptheria, can facilitate the killing of pathogenic bacteria, and can protect against viral infection of cells. The ability to specifically immunize and provide protection against infectious disease has had a major impact on public health. Indeed a coor

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New Concepts in Antibody Structure structure of enzyme-substrate complexes. X-ray crystallographic analysis of enzymes and their substrates have given us ample evidence for the existence of pockets or tunnels in which substrates enter and undergo enzymatically mediated chemical changes. This view has greatly influenced the models fo