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Titlebook: Antibiotic Resistance Methods and Protocols; Stephen H. Gillespie Book 20011st edition The Editor(s) (if applicable) and The Author(s), un

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期刊全称Antibiotic Resistance Methods and Protocols
影响因子2023Stephen H. Gillespie
视频video
发行地址Includes supplementary material:
学科分类Methods in Molecular Medicine
图书封面Titlebook: Antibiotic Resistance Methods and Protocols;  Stephen H. Gillespie Book 20011st edition The Editor(s) (if applicable) and The Author(s), un
影响因子At a time of rising concern about drug resistance and falling output of new antibacterial compounds, antibiotic research has once again returned to the forefront of medical science. In Antibiotic Resistance: Methods and Protocols, Stephen Gillespie and a panel of leading clinical and diagnostic microbiologists describe a series of detailed molecular and physical methods designed to study the growing problem of antibiotic resistance, as well as facilitate new antibiotic research programs for its effective redress. The techniques range widely from those that provide rapid diagnosis via DNA amplification and phage display, tothose for plotting the transmission of resistant organisms and investigating their epidemiology. The methods are readily adaptable to a wide range of resistant bacterial organisms. In order to ensure successful results, each method is described in minute detail and includes tips on avoiding pitfalls..Practical and wide-ranging, Antibiotic Resistance: Methods and Protocols provides a collection of indispensable techniques not only for illuminating the basic biology of antimicrobial resistance, but also for developing and implementing new diagnostic and epidemiologi
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Quantification of M. tuberculosis DNA in Sputum During the Treatment of Pulmonary Tuberculosis.). Once effective treatment has been initiated, DNA levels remain high in comparison to viable MTB counts in a majority of smear-positive patients and thus do not serve as a marker for the bactericidal response observed in sputa.
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Diskrete Wahrscheinlichkeitsverteilungenof peptidoglycan synthesis, detection, and quantitation of MMP is useful for the investigation of how the cell-wall synthesis system is altered in . in association with glycopeptide resistance. For example, the cytoplasmic pool size of MMP is several times greater in Mu50 and Mu3 than in vancomycin-susceptible . strains (.).
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https://doi.org/10.1007/978-3-0348-5874-8th these nucleic acid targets, bacterial mRNA is typically shortlived with a half-life of only a few minutes (., .). Consequently, an mRNA based assay is likely to detect only living organisms and thus be a good indicator of bacterial viability and therefore therapeutic response (., ., .).
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Book 20011st editione forefront of medical science. In Antibiotic Resistance: Methods and Protocols, Stephen Gillespie and a panel of leading clinical and diagnostic microbiologists describe a series of detailed molecular and physical methods designed to study the growing problem of antibiotic resistance, as well as fa
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