Titlebook: Antibiotic Resistance; Anthony R.M. Coates Book 2012 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-

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Surveillance Programmes and Antibiotic Resistance: Worldwide and Regional Monitoring of Antibiotic stitutional and industry or pharmaceutical led surveillance programmes is essential. This chapter describes the resistance issue, factors affecting this issue and examples of such ongoing resistance surveillance programmes.

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Antibiotics in Phase II and III Clinical Trials,covered. The shortage of compounds in development for Gram-negatives and the small number of new classes in the pipeline is of serious concern; this matter needs to be addressed by governments, the regulatory authorities, the pharmaceutical industry and academia urgently.

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Book 2012istance and the decrease in the rate of replacement of redundant compounds. The origins of antibiotic resistance are then described. It is proposed that there is a large bacterial resistome which is a collection of all resistance genes and their precursors in both pathogenic and non-pathogenic bacte

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https://doi.org/10.1007/978-3-7091-3608-9stitutional and industry or pharmaceutical led surveillance programmes is essential. This chapter describes the resistance issue, factors affecting this issue and examples of such ongoing resistance surveillance programmes.

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