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Titlebook: Antibiotic Resistance; Anthony R.M. Coates Book 2012 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-

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https://doi.org/10.1007/978-3-662-36782-7tolerance is temporary, reversible, and associated with slowing of the multiplication rate. Secondly, bacteria can undergo genetic mutations leading to permanent clonal resistance to antimicrobial agents. In patients with infections, nonmultiplying bacteria, some of which may be viable but noncultur
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,Der Gelenk- oder Gerberträger,iotics capable of eradicating an infection. All pathogens produce a small subpopulation of dormant persister cells that are highly tolerant to killing by antibiotics. Once an antibiotic concentration drops, surviving persisters re-establish the population, causing a relapsing chronic infection. Pers
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Einige weitere statisch bestimmte Systeme,get for antimicrobial therapy and the development of new antibacterials to address the efflux problem..Tigecycline is an example of how old antibiotics, in this case tetracyclines, which have become substrates for efflux pumps, can be extensively modified to restore antimicrobial activity and clinic
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