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Titlebook: Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis; Renato Alberto Sinico,Loïc Guillevin Book 2020 Springer Nature Switzerl

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https://doi.org/10.1007/3-540-35122-1g ANCA in >30–90% of the affected patients. Granulomatosis with polyangiitis (GPA, formerly Wegener’s granulomatosis), eosinophilic granulomatosis with polyangiitis (EGPA, formerly Churg–Strauss syndrome), and microscopic polyangiitis (MPA) are AAVs [1]. Renal-limited vasculitis, another AAV, is a b
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Renato Alberto Sinico,Loïc GuillevinWritten by well-known experts in the field.Presents updates with regard to rare disorders.Addresses to specialists in different diseases
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Rare Diseases of the Immune Systemhttp://image.papertrans.cn/a/image/158348.jpg
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Introduction: Nomenclature and Classificationiple patterns of injury, diverse known etiologies and pathogenic mechanisms, absence of known etiologies and pathogenic mechanisms in some forms of vasculitis, and the myriad overlapping and nonspecific signs and symptoms caused by vasculitides. The goals of nomenclature, classification, and diagnos
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Etiopathogenesis of ANCA-Associated Vasculitisher MPO or PR3 proteins play a key role. Molecular mimicry through bacterial antigens, the presentation of peptides complementary to PR3, and the presentation of MPO and PR3 proteins through NETs can induce the production of anti-MPO or anti-PR3 autoantibodies, especially in the context of TH17/Treg
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ANCA: Methods and Clinical Significanceculitis (AAV). Such autoantibodies may also be detected in a wide range of inflammatory and infectious diseases leading to a critical reappraisal in the diagnostic significance. ANCA-associated vasculitides are a heterogeneous group of rare syndromes characterized by necrotizing inflammation of smal
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Activity and DamageA major factor in defining optimal therapy and in measuring the success or failure of therapy is careful evaluation of each case. There are no simple measurements to define disease activity or response to treatment. A combination of a structured clinical assessment together with key laboratory measu
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