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Titlebook: Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis; Renato Alberto Sinico,Loïc Guillevin Book 2020 Springer Nature Switzerl

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发表于 2025-3-21 17:05:01 | 显示全部楼层 |阅读模式
期刊全称Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis
影响因子2023Renato Alberto Sinico,Loïc Guillevin
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发行地址Written by well-known experts in the field.Presents updates with regard to rare disorders.Addresses to specialists in different diseases
学科分类Rare Diseases of the Immune System
图书封面Titlebook: Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis;  Renato Alberto Sinico,Loïc Guillevin Book 2020 Springer Nature Switzerl
影响因子.This volume, written by well-known experts in the field, covers all aspects of Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV). The expression refers to a group of diseases, characterized by destruction and inflammation of small vessels. The clinical signs vary and affect several organs, such as the kidney, lung, skin, nervous system and others..The opening chapters give some historical hints, explain the genetic basis of the disease and provide insights into the pathogenesis derived from recent experimental studies and guides the reader through classification and nomenclature. A large part of the book is then devoted to a detailed description of the specific related diseases and their clinical presentations, the disease course, and potential complications. The advice regarding treatment is based on the best currently available evidence in this constantly evolving area...The book is part of Springer’s series Rare Diseases of the Immune System, which presents recently acquired knowledge on pathogenesis, diagnosis, and therapy with the aim of promoting a more holistic approach to these conditions. AAVs are systemic autoimmune diseases of unknown cause that af
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Introduction: Nomenclature and Classificationation and diagnosis of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Physicians and scientists have made remarkable advances in the classification and diagnosis of vasculitides since the seminal observations in the 1800s; however, validated and widely applied classification
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Genetics of ANCA-Associated Vasculitis in complex susceptibility loci and disease mechanisms. Finally, we discuss the limitations of current methods and the challenges that we still have to approach in order to translate genomic and epigenomic data into clinical practice.
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ANCA: Methods and Clinical Significanceoassays for PR3-ANCA and MPO-ANCA. New guidelines for ANCA testing have been developed based on a recent European multicenter study, and according to the revised 2017 international consensus recommendations, testing for ANCA in small-vessel vasculitis can be done by PR3-ANCA and MPO-ANCA immunoassay
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Granulomatosis with Polyangiitisccurring within 1 year of the first symptoms. With current treatments, which include first an induction phase, based on the combination of corticosteroids and an immunosuppressant, then a maintenance treatment phase, remission can be achieved in more than 80% of cases. However, the relapse-free surv
发表于 2025-3-23 03:44:25 | 显示全部楼层
Microscopic Polyangiitiseart disease..Anti-neutrophil cytoplasmic antibodies, usually P-ANCA/MPO-ANCA, are detected in up to 80–90% of patients with active MPA..Untreated MPA has an unfavorable course and is associated with increased mortality and end-stage renal disease (ESRD). Factors independently related to death are t
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