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Titlebook: Anti-Idiotypic Vaccines; P.-A. Cazenave Book 1991 Springer-Verlag New York Inc. 1991 Antigen.cell.genes.parasite.parasites.research.vaccin

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发表于 2025-3-21 18:15:56 | 显示全部楼层 |阅读模式
期刊全称Anti-Idiotypic Vaccines
影响因子2023P.-A. Cazenave
视频video
学科分类Progress in Vaccinology
图书封面Titlebook: Anti-Idiotypic Vaccines;  P.-A. Cazenave Book 1991 Springer-Verlag New York Inc. 1991 Antigen.cell.genes.parasite.parasites.research.vaccin
影响因子Vaccines have historically been considered to be the most cost-effective method for preventing communicable diseases. It was a vaccine~hat enabled global eradication of the dreaded disease smallpox. Mass immunization of children forms the anchor of the strategy of the World Health Organization (WHO) to attain "health for all" status by the year 2000. Vaccinology is undergoing a dimensional change with the advances that have taken place in immunology and genetic engineering. Vaccines that confer short or inadequate immunity or that have side effects are being replaced by better vaccines. New vaccines are being developed for a variety of maladies. Monoclonal antibodies and T cell clones have been employed to delineate the immunodeterminants on microbes, an approach elegantly complemented by computer graphics and molecular imaging techniques. Possibilities have opened for obtaining hitherto scarce antigens of parasites by the DNA recombinant route. Better appreciation of the idiotypic network has aroused research on anti-idiotypic vaccines. Solid-phase synthesis of peptides is leading to an array of synthetic vaccines, an approach that is expected to attain its full potential once the
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发表于 2025-3-21 22:46:47 | 显示全部楼层
Anti-Idiotypic Vaccines for Carbohydrate Antigens,ti-idiotype might behave as an internal image of antigen or Ab2β (1). The criteria I will use to determine whether an anti-idiotype is an internal image are those first discussed with reference to vaccines by Nisonoff and colleagues (2, 3).
发表于 2025-3-22 04:10:45 | 显示全部楼层
0941-875X nabled global eradication of the dreaded disease smallpox. Mass immunization of children forms the anchor of the strategy of the World Health Organization (WHO) to attain "health for all" status by the year 2000. Vaccinology is undergoing a dimensional change with the advances that have taken place
发表于 2025-3-22 08:10:06 | 显示全部楼层
https://doi.org/10.1007/978-3-540-74452-8o an idiotypic site cross-reacting with that determinant, and for which we propose the name of homobody. Accordingly, antigenic determinants are projected into the world of immunoglobulin molecules in two manners: as negative images, these define antibodies; as positive images, these define homobodies.
发表于 2025-3-22 10:57:41 | 显示全部楼层
Idiotype Vaccines by Antibody Engineering: Structural and Functional Considerations,o an idiotypic site cross-reacting with that determinant, and for which we propose the name of homobody. Accordingly, antigenic determinants are projected into the world of immunoglobulin molecules in two manners: as negative images, these define antibodies; as positive images, these define homobodies.
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发表于 2025-3-23 00:31:51 | 显示全部楼层
Einführung in die Kryptographie this model system we were able to specifically determine the receptor interaction sites by sequence homology with the viral hemagglutinin. Based on these sequences we produced functionally active mimics that interfere with virus binding and maintain, when suitably constructed, many properties of the hemagglutinin.
发表于 2025-3-23 01:53:48 | 显示全部楼层
,Utilization of Anti-Idiotypic Antibodies as Molecular Probes of Virus—Receptor Interaction, this model system we were able to specifically determine the receptor interaction sites by sequence homology with the viral hemagglutinin. Based on these sequences we produced functionally active mimics that interfere with virus binding and maintain, when suitably constructed, many properties of the hemagglutinin.
发表于 2025-3-23 07:07:44 | 显示全部楼层
Book 1991bal eradication of the dreaded disease smallpox. Mass immunization of children forms the anchor of the strategy of the World Health Organization (WHO) to attain "health for all" status by the year 2000. Vaccinology is undergoing a dimensional change with the advances that have taken place in immunol
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