Titlebook: Annual Update in Intensive Care and Emergency Medicine 2021; Jean-Louis Vincent Book 2021 The Editor(s) (if applicable) and The Author(s),

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Observation of Leukocyte Kinetics Using Handheld Vital Microscopes During Surgery and Critical Illne, ischemia/reperfusion injury and cardiac surgery. Monitoring of microcirculatory leukocytes is a potential candidate tool to assess the inflammatory and pathophysiological status of the patient at the bedside. In the last few years, new methodologies have been introduced using hand-held vital micro

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Tracheostomy for COVID-19: Evolving Best Practicery support, and it is no surprise that the COVID-19 pandemic has seen a rapid increase in the use of tracheostomy in the critically ill, rising from around 12% to around 20% of all ventilated admissions. The pandemic has thrown a spotlight onto existing and unanswered questions around tracheostomy c

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Helmet Non-invasive Ventilation in Acute Hypoxemic Respiratory Failure Due to COVID-19e need for invasive mechanical ventilation. Other potential advantages of the helmet interface include better patient tolerability and decreased risk of aerosolization. However, limited data are currently available to guide its clinical use. The objective of this article is to review the current evi

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https://doi.org/10.1007/978-88-470-0609-6ased expression of the human leukocyte antigen (HLA)-DR on CD14-monocytes with simultaneous maintenance of monocyte capacity for the production of pro-inflammatory cytokines. The concept of severe COVID-19 as a situation of cytokine storm led early to the use of anakinra and tocilizumab as strategie

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12 Bezüge zu Irrungen, Wirrungen affecting the cytosolic calcium (Ca.) and/or myofilament function and cardiac contractile force. Mitochondrial function is also significantly impacted by sepsis. These broad-spectrum micro derangements are associated with even greater variation in macroscopic heart dysfunction patterns, although fi

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