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Titlebook: Animals and Alternatives in Toxicology; Present Status and F Michael Balls (Professor of Medical Cell Biology), Textbook 1991Latest edition

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期刊全称Animals and Alternatives in Toxicology
期刊简称Present Status and F
影响因子2023Michael Balls (Professor of Medical Cell Biology),
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图书封面Titlebook: Animals and Alternatives in Toxicology; Present Status and F Michael Balls (Professor of Medical Cell Biology), Textbook 1991Latest edition
影响因子This volume considers the second report of the FRAME Toxicity Committee presenting reviews and discussions by invited authors and general discussions. It covers developments in toxicology and the use of non-animal methods in toxicity testing since the first report, published in 1983; it highlights the need for rationalisation and harmonisation of regulatory guidelines for more critical attitudes toward currently accepted animal tests and for more attention to be focussed on non-animal alternatives; how to inform scientists of alternatives to animals; and how to develop and integrate non-animal alternatives. The book is a key document in the development, validation, and use of non-animal methods and is aimed at toxicologists, pharmacologists, and policy-makers in academia, industry and government.
Pindex Textbook 1991Latest edition
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Genotoxicity Testing,us prevent this disease with its vast social, human and economic costs (1). Whilst the disease has been recognised for many centuries, we are no nearer to making significant inroads into improving a patient’s prognosis for the majority of solid tumours, so cancer prevention should be a major goal.
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Alternative Methods and Their Application in Neurotoxicity Testing,se (1). Up to 1,000 new chemicals enter commerce each year, so it is impossible for populations of living organisms, including man, to avoid exposure to chemicals in some form or another. The existence of this extensive chemical universe, plus the fact that some chemicals are highly toxic to biologi
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The Future of Alternative Approaches in Reproductive Toxicity Testing,ttention was given to compliance with the Three Rs in current testing methods and the achievement of reduction, refinement and replacement in animal testing by both current methods and research development. This report will comprise three sections covering regulatory aspects, . and . prescreens, and
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The Development, Validation and Acceptance of , Toxicity Tests,ests for mutagenicity (2, 3) and for biologically-active mineral dusts (4), it was difficult to find any collaborative interlaboratory attempts to establish the reliability and usefulness of . methods in toxicity testing (5). For this reason, FRAME established a research programme, which at that tim
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Future Developments in , Methodology, toxicology and in the search for . methods for predicting the toxicological effects of chemicals and products. Major research programmes are under way in the industrial and academic research laboratories of many countries, and a number of . methods are already in use as screening tests. Such screen
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Economic Ideas You Should Forgetpotentially centrally-active and neurotoxic xenobiotics are continually entering the development ‘pipeline’ in industry. To identify neurotoxic chemicals and then legislate their use in society, previous and current emphasis is on the use of . methodology. The purpose of this review is to identify t
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Michael Balls (Professor of Medical Cell Biology),
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