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Titlebook: Angiogenesis in Health, Disease and Malignancy; Ali Salajegheh Book 2016 Springer International Publishing Switzerland 2016 Gene function.

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楼主: Corrugate
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Cysteine-Rich 61 (CYR61),cellular regulatory factors, which are involved in internal and external signalling of the cell. CYR61 is a secreted, heparin-binding protein that is encoded by the CYR61 gene. The CYR61 protein contains a highly preserved cysteine-rich primary sequence that is organised into discrete domains simila
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Erythropoietin-Producing Hepatocellular Receptors A: Ephrin A1, Ephrin A2 and Ephrin A3,, rearrangement during neuronal, vascular and epithelial development, signalling between cells and many more are the Receptor Tyrosine Kinases (RTK); specifically, Erythropoietin-producing hepatocellular receptors, or Eph receptors, which contain tyrosine kinase domains. They have a high binding aff
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Erythropoietin-Producing Hepatocellular Receptors B: Ephrin B2, Ephrin B4,fically, the ephrin family mediates embryonic growth processes such as axon guidance, boundary formation and cell migration. While during adulthood, the key targets comprise nervous system function including potentiation, central and peripheral stem cell differentiation and angiogenesis. Ephrin-B2 i
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Ets-1,ement in a range of physiological and pathological processes has been studied. Ets-1 is involved in a wide range of biological functions. Transcription factors are responsible for the regulation of specific genes and thus have vital roles in controlling cell function. The ETS family of transcription
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Fibrin,en associated in angiogenesis during tissue repair, with fibrin matrices acting as a seal and scaffold for directing tissue repair. After injury, platelets possessing thrombin receptors move to the site and bind with the available thrombin molecules in the serum. The activated thrombin then converts
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Fibroblast Growth Factors (Acidic: FGF-1; Basic: FGF-2) and Its Receptors (FGFR),) which are situated in the extracellular matrix on the surfaces of most cells. This pool of FGFs acts as a reservoir for regulatory growth factors which are released in a regulated manner by heparanases. Members of FGFs from FGF-1 to FGF-10 bind to high-affinity tyrosine kinase FGF receptors (FGFR)
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Fibronectin,bronectin is also important as a regulator in the process of remodelling in extracellular matrix. In normal situation fibronectin is involved in the process of tissue repair and helps the formation of clot. Elevation of cellular fibronectin and persistent production of extracellular matrix have been
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Introduction to Angiogenesis in Normal Physiology, Disease and Malignancy,rs to disease and malignancy, cancer proliferation and progression will be discussed. New insights into the role of angiogenesis and the therapeutic inhibition of its regulators will be investigated due to the great potential for exploitation in the development of a novel treatment for cancer.
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