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Titlebook: Analytical Techniques in the Pharmaceutical Sciences; Anette Müllertz,Yvonne Perrie,Thomas Rades Book 2016 Springer Science+Business Media

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期刊全称Analytical Techniques in the Pharmaceutical Sciences
影响因子2023Anette Müllertz,Yvonne Perrie,Thomas Rades
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发行地址A ‘must-have’ handbook for inclusion in laboratories working in the field of drug delivery, controlled release, and pharmaceutical sciences.Includes protocols that can be adopted by researchers and th
学科分类Advances in Delivery Science and Technology
图书封面Titlebook: Analytical Techniques in the Pharmaceutical Sciences;  Anette Müllertz,Yvonne Perrie,Thomas Rades Book 2016 Springer Science+Business Media
影响因子The aim of this book is to present a range of analytical methods that can be used in formulation design and development and focus on how these systems can be applied to understand formulation components and the dosage form these build. To effectively design and exploit drug delivery systems, the underlying characteristic of a dosage form must be understood--from the characteristics of the individual formulation components, to how they act and interact within the formulation, and finally, to how this formulation responds in different biological environments. To achieve this, there is a wide range of analytical techniques that can be adopted to understand and elucidate the mechanics of drug delivery and drug formulation. Such methods include e.g. spectroscopic analysis, diffractometric analysis, thermal investigations, surface analytical techniques, particle size analysis, rheological techniques, methods to characterize drug stability and release, and biological analysis in appropriate cell and animal models. Whilst each of these methods can encompass a full research area in their own right, formulation scientists must be able to effectively apply these methods to the delivery system
Pindex Book 2016
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Fluorescence Spectroscopy: Basic Foundations and Methodsdevelopments on distinct fluorescence methods, particularly those related to the study of biological phenomena. This chapter discusses the foundations of the fluorescence phenomenon, introduces some general methodologies and provides selected examples on applications focused to disentangle structura
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Raman Spectroscopyed along with some of the key issues in measuring Raman spectra that may be relevant to pharmaceutical samples. The limitations and strengths of different instruments (dispersive and Fourier-transform) are described. The use of Raman spectroscopy is highlighted in a number of case studies that utili
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Pharmaceutical Terahertz Spectroscopy and Imaging systems. In this chapter the technology that has enabled the recent surge of interest in using terahertz techniques is explained in terms of its basic principles and the specific implementations of pharmaceutical relevance. Using a number of examples and case studies an overview of the current stat
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Circular Dichroism Spectroscopy for Structural Characterization of Proteins First, the native structure of a given protein drug molecule must be characterized in order to define the active compound. Next, for the successful development of a formulation or drug delivery system for said molecule, compatibility of the system with the protein should be demonstrated. This is a
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Applications of Mass Spectrometry in Drug Development Scienceo a premier analytical tool in drug development science. Through specific MS-based workflows including customized sample preparation, coupling to liquid chromatography and different ionization principles, both qualitative and quantitative analysis of small and large drug compounds can be achieved at
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Applications of Small Angle X-ray Scattering in Pharmaceutical Science. This contribution aims to highlight a range of areas in which SAXS can be deployed to better understand structure in pharmaceutically relevant materials from molecular to colloidal dimensions, with a focus on developing synchrotron techniques that provide new opportunities in time resolved kinetic
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