Titlebook: Analytical Techniques in the Pharmaceutical Sciences; Anette Müllertz,Yvonne Perrie,Thomas Rades Book 2016 Springer Science+Business Media

影响带来

Handlungskonzepte in disruptiver Innovation,ch it can be used to probe crystal structures, with a particular emphasis on the practicalities of data collection in the laboratory and on data analysis, leading ultimately to high-quality, refined crystal structures.

假设

Thomas W. Flanagan,Charles D. Nicholsd will be discussed. The use of AF4 for protein pharmaceuticals as well as particulate systems will be described and some examples given in the literature will be presented. Finally, a summary of the most recent trends in AF4 and an outlook will be given for potential application fields in the future.

不妥协

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entrance

https://doi.org/10.1007/978-1-4614-3058-2l arrangements are defined and applications to pharmaceutical analyses are discussed. Applications discussed progress from preformulation characterization, through stability testing and amorphous content quantification to analyses of formulated products.

变形词

Pharmaceutical Terahertz Spectroscopy and Imagingquantification, detailed analysis of phase transitions to amorphous stability. Important imaging applications include non-destructive coating thickness measurements, characterisation of the microstructure of tablet matrices as well as liquid transport into tablets during disintegration.

appall

Single-Crystal X-ray Diffractionspects that, in the author’s opinion, should still be understood to measure crystallographic data effectively and to interpret crystallographic results. The focus is on selected topics that are likely to be most relevant to pharmaceutical solid-form characterization.

高歌

Isothermal Microcalorimetryl arrangements are defined and applications to pharmaceutical analyses are discussed. Applications discussed progress from preformulation characterization, through stability testing and amorphous content quantification to analyses of formulated products.

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Raman Spectroscopyze multivariate techniques; polymorphism, drug delivery and counterfeit drug studies are described. Finally, new technologies that are set to further enhance Raman spectroscopy as a method for analysis, such as low frequency Raman, spatially offset Raman scattering, transmission Raman and spatial heterodyne Raman spectroscopy are discussed.