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Titlebook: An Antigen Depository of the Immune System: Follicular Dendritic Cells; Marie H. Kosco-Vilbois Book 1995 The Editor(s) (if applicable) and

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https://doi.org/10.1007/978-3-662-26166-8. Accessory cells are known to collaborate with lymphocytes and enable them to carry out their essential functions. FDC present antigen (Ag) to B cells and facilitate B cell functions; they may be thought of as B cell-associated accessory cells. In contrast, other dendritic cells, including Langerha
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https://doi.org/10.1007/978-3-662-26166-8issues. During T cell-dependent humoral immune responses, B cells undergo proliferation, somatic mutation, isotype switching, positive selection, and differentiation into memory B cells and plasma cells within the FDC networks (B. 1992; K. and G. 1992; K. et al. 1987; L. et al. 1992; M. 1994; N. 199
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https://doi.org/10.1007/978-3-662-26166-8n has been paid to the preference of the virus for specific cells. However, the preference of HIV-1 for specific host tissues or tissue compartments such as germinal centers (GC) of the lymphoid tissue was often overlooked. Application of electronmicroscopic, immunohistochemical, and nucleic acid hy
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https://doi.org/10.1007/978-3-642-66144-0lized persistent lymphadenopathy was considered as one of the symptoms in this condition. The atypical histologic features of the lymph nodes, mainly the hyperplasia of follicles, were also identified at that time. After the discovery of HIV-1 and the introduction of serology to assess the status of
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https://doi.org/10.1007/978-3-642-66144-0multinucleate cells, called Reed-Sternberg cells, which are scattered irregularly throughout Hodgkin’s infiltrates. Intermingled with the Reed-Sternberg cells is a mixed population of lymphocytes, histiocytes, eosinophils, plasma cells, and neutrophils. Histological subclassification of Hodgkin’s di
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A Theory of Follicular Dendritic Cell Origin,rimitive reticular cells (K. et al. 1978; G. 1980; H. et al. 1980a,b; I. et al. 1983; D. etal. 1984; H. etal. 1984) or from mesenchymal cells (pericytes around capillaries) found locally in follicles (R. etal. 1988). In early studies, FDC were identified as a reticular cell type (M. and A. 1965; S.
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Mechanism of Immune Complex Trapping by Follicular Dendritic Cells,operty of binding antigens in the form of antigen-antibody complexes and retaining these complexes, without ingestion, for long periods of time. The presence of antigen-antibody complexes, also called immune complexes, on FDC is believed to play a crucial role in the development of B cell memory and
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