Titlebook: Amino Acid Biosynthesis – Pathways, Regulation and Metabolic Engineering; Volker F. Wendisch Book 2007 Springer-Verlag Berlin Heidelberg 2

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,Allgemeines, Häufigkeit, Ausbreitung,rresponding. metabolism. This review intends to summarize the currentknowledge on methionine biosynthesis in these organisms and discusses approaches for the construction ofmethionine producer strains.

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,Allgemeines, Häufigkeit, Ausbreitung,al mechanisms are involved in the control of the intracellular concentration of cysteine, which is a highly reactive compound due to its –SH group. This amino acid is degraded mainly by cysteine desulfhydrases or is excreted by exporters. A large variety of molecular mechanisms participate in fine-t

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https://doi.org/10.1007/978-3-642-90806-4utamate kinase (NAGK) to be functional. In most organisms, the acetyl group ofacetylornithine is either split by an acetylornithinase (AO) or recycled on glutamate by OAT; in both cases,one of the products is ornithine which is carbamoylated into citrulline. In some Proteobacteria however,acetylorni

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https://doi.org/10.1007/978-3-663-02178-0operties of specific amino acid excretion systems in thesetwo organisms, in particular those responsible for efflux of lysine (and arginine), threonine, branchedchain amino acids, cysteine (and cysteine derivatives) and glutamate are described. A complete listof all secondary and primary transport s

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https://doi.org/10.1007/978-3-658-24338-8bolomics to gather biological data, and megabase molecular biology tools toengineer at will these organisms at various scales, from the level of single base pairs to that of chromosomes.Systems biology represents the next technological paradigm necessary on the one hand to efficiently integrateand p

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The ,-Lysine Story: From Metabolic Pathways to Industrial Production,edin effective biotechnological processes currently used for producing about 750 000 tons of lysineper year. Today, systems-oriented approaches aiming at investigating the link between the different componentsof cellular physiology such as transcriptome, fluxome and metabolome, provide a novel power

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Aromatic Amino Acids,ay are strictly regulated by feedback inhibition, repression and partly throughattenuation (in .).. .-Tryptophan and .-phenylalanineare essential amino acids for man and most livestock. Main microbial producer strains are .and .. Strain development includes alleviationof the various regulatory level

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