Titlebook: Alzheimer’s Disease: Lessons from Cell Biology; K. S. Kosik (Associate Professor of Neurology and Conference proceedings 1995 Springer-Ve

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https://doi.org/10.1007/978-3-658-21031-1se amyloid, can be unremarkable, and neurofibrillary tangles often occur at sites anatomically distant from plaques..We have found that a secreted fragment of APP can stimulate the mitogen-activated protein kinase (MAPK) in a ras-dependent manner and that stimulation along this pathway results in th

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K. S. Kosik (Associate Professor of Neurology and

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0945-6066 e disease in 1907, the science of Alzheimer‘s disease was descriptive, and lay in the province of pathologists. This time period, during which a great deal was 978-3-642-79425-4978-3-642-79423-0Series ISSN 0945-6066 Series E-ISSN 2196-310X

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Regulation of Receptor Trafficking by ras-Like GTPases,ional transport vesicles in cells expressing rab9 S21N protein. This is a surprise, since rab proteins are believed to facilitate transport vesicle targeting and/or fusion. Our findings suggest that transport vesicle formation is regulated by the availability of transport factors assembled in some f

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