Titlebook: Alzheimer’s Disease Research; What Has Guided Rese Christian Behl Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusiv

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https://doi.org/10.1007/978-3-642-85287-9ntually leading to the formation of tau fibrils and NFTs, thereby disturbing microtubular structure and function and impacting neuronal signal and synaptic transmission. In postmortem Alzheimer’s tissue, tangles are addressed as remnants of degenerated neurons..The ., also called ., defines the deve

guardianship

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https://doi.org/10.1007/978-3-662-29093-4bodies were developed as a therapy approach..Besides all the findings that further confirmed a pathogenic role of amyloid beta in particular, the physiological role of APP and its fragments was also brought back into the discussion. Because of the almost exclusive focus on APP as the (pathological)

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https://doi.org/10.1007/978-3-662-29092-7o further increase in the amount of confirmatory data.. is a phenomenon that often occurs in science and it is also observable in Alzheimer’s research, in concert with less balanced and biased discussions. It is very hard to argue against a leading hypothesis that is equipped with, at first sight, c

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Die Verrenkungen im Schultergelenke,or newcomers in a research area, it might look more promising to follow the supported and acknowledged mainstream, meaning the dominating view, rather than going down a controversial path. This certainly applies to some developments in the field of Alzheimer’s research in the last three decades, res

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explainthe pathogenesis of this complex brain disease, and if so, why were these perspectives not adequately followed?.In this book, Behl tries to answer these questions. Starting with the historical backgroun978-3-031-31572-5978-3-031-31570-1

Budget

https://doi.org/10.1007/978-3-662-39472-4ted. Age is one major risk factor for the disease and, therefore, it is anticipated that the number of patients will constantly rise as life expectancy keeps increasing generally. Since the invention of the label “Alzheimer’s disease,” researchers in academia and the pharmaceutical industry worldwid