Titlebook: Aging Research in Yeast; Michael Breitenbach,S. Michal Jazwinski,Peter Laun Book 2012 Springer Science+Business Media B.V. 2012 Aging.Cell

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The Role of Mitochondria in the Aging Processes of Yeast,ive capacity of mother cells, while chronological aging occurs in postmitotic cells that are under starvation conditions in stationary phase leading to loss of viability, as discussed elsewhere in this book. In so doing we also give an overview of the similarities and dissimilarities of the various

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The Retrograde Response and Other Pathways of Interorganelle Communication in Yeast Replicative Agie retrograde response. The involvement of TOR brings another large family of signaling events into juxtaposition. Ceramidesynthesis is regulated by TOR opening up the potential for coordination of mitochondrial status with a wide array of additional cellular processes. The retrograde response lies a

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Aging and the Survival of Quiescent and Non-quiescent Cells in Yeast Stationary-Phase Cultures,me-scale analyses of yeast stationary-phase cultures have identified two major cell fractions: quiescent and non-quiescent, which we discuss in detail in this chapter. We review evidence that cell populations isolated from these cultures exhibit population-specific phenotypes spanning a range of met

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DNA Damage and DNA Replication Stress in Yeast Models of Aging,that defects in DNA replication might contribute to chronological aging appears to be somewhat paradoxical. However, the results of recent studies suggest that a significant fraction of cells in stationary phase cultures are not quiescent, especially in experiments that employ defined medium, which

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Cellular Homeostasis in Fungi: Impact on the Aging Process,ases that bind and degrade abnormally modified and / or aggregated mitochondrial proteins. The second level is concerned with maintaining the quality of whole mitochondria. Among the pathways of this level are mitochondrial dynamics and autophagy (mitophagy). Mitochondrial dynamics describes the tim