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Titlebook: Aging Research in Yeast; Michael Breitenbach,S. Michal Jazwinski,Peter Laun Book 2012 Springer Science+Business Media B.V. 2012 Aging.Cell

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发表于 2025-3-21 17:08:51 | 显示全部楼层 |阅读模式
期刊全称Aging Research in Yeast
影响因子2023Michael Breitenbach,S. Michal Jazwinski,Peter Laun
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发行地址Yeast aging research and its relevance to humans.Thorough account of a rapidly expanding field.Offers a molecular cell biology perspective on aging.Written by authorities in the field of aging researc
学科分类Subcellular Biochemistry
图书封面Titlebook: Aging Research in Yeast;  Michael Breitenbach,S. Michal Jazwinski,Peter Laun Book 2012 Springer Science+Business Media B.V. 2012 Aging.Cell
影响因子This volume includes contributions by the leading experts in the field of yeast aging. Budding yeast (Saccharomyces cerevisiae) and other fungal organisms provide models for aging research that are relevant to organismic aging and to the aging processes occurring in the human body. Replicative aging, in which only the mother cell ages while the daughter cell resets the clock to zero is a model for the aging of stem cell populations in humans, while chronological aging (measured by survival in stationary phase) is a model for the aging processes in postmitotic cells (for instance, neurons of the brain). Most mechanisms of aging are studied in yeast. Among them, this book discusses: mitochondrial theories of aging, emphasizing oxidative stress and retrograde responses; the role of autophagy and mitophagy; the relationship of apoptosis to aging processes; the role of asymmetric segregation of damage in replicative aging; the role of replication stress; and the role of the cytoskeleton in aging. Modern methods of yeast genetics and genomics are described that can be used to search for aging-specific functions in a genome-wide unbiased fashion. The similarities in the pathology of senes
Pindex Book 2012
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https://doi.org/10.1007/978-3-030-28622-4hemistry has provided the opportunity to analyse in some detail how reactive oxygen and nitrogen species arise in cells, how cells respond to the damage that these reactive species cause, and to begin to dissect how these species may be involved in the ageing process. This chapter reviews the major
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Proselytization as a Nationalist Projecthondrial theory of aging”. Mitochondria are the major source of ATP in the eukaryotic cell but are also a major source of reactive oxygen species (ROS) and play an important role in the process of apoptosis and aging. We are discussing the mitochondrial theory of aging (TOA), its origin, similarity
发表于 2025-3-22 08:09:49 | 显示全部楼层
Proselytization as a Nationalist Projectd by experimentally-induced mitochondrial dysfunction , but it also is activated during the course of normal replicative aging, allowing yeast to have as long a replicative life span as they do. The components of the retrograde signaling pathway participate in diverse cellular processes such as mito
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Convex Functions of One Real Variable,g mechanisms of aging and longevity. The long-term viability of non-dividing cells, known as chronological longevity, relies on cellular processes that degrade old components and replace them with new ones. Key among these processes is amino acid homeostasis. Amino acid homeostasis requires three pr
发表于 2025-3-23 01:01:03 | 显示全部楼层
Subdifferentials of Finite Convex Functions,complex organisms, only a relatively few studies have investigated DNA damage as an aging factor in the model organism .. Several of these studies point to DNA replication stress as a cause of age-dependent DNA damage in the replicative model of aging, which measures how many times budding yeast cel
发表于 2025-3-23 01:26:14 | 显示全部楼层
Convex and Stochastic Optimizations a destructive process leading to the death of single cells, also serves as a pro-survival mechanism that ensures healthy organismal development and acts as a life-prolonging or anti-aging program. The discovery that yeast also possess a functional and, in many cases, highly conserved apoptotic mac
发表于 2025-3-23 08:43:05 | 显示全部楼层
Convex and Stochastic Optimizationre usually highly detrimental. Functional impairments of cell components can lead to diseases and in extreme cases to organismal death. Dysfunction of cells can be induced by a number of toxic by-products that are formed during metabolic activity, like reactive oxygen and nitrogen species, for examp
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