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Titlebook: Advantages and Problems with Non-Opioids in Pain Management; Vancouver, Canada, A Michael J. Parnham Conference proceedings 1997 Birkhäuser

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Introduction,Effective though they are in the treatment of a wide variety of painful conditions, opioids are not always the most suitable analgesic therapy. Tried and tested non-opioid analgesics are frequently preferable, especially for the treatment of mild to moderate pain, because of their lower incidence of side-effects or more relevant sites of action.
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Non-opioids in cancer pain management,With all the elegant delivery forms now available for opioids in the treatment of cancer pain, it may seem to some that non-opioids have little place in the management of pain for this indication. This impression requires correction.
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Overview: 978-3-7643-5678-1978-3-0348-8865-3
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https://doi.org/10.1007/978-981-99-1098-4c efficacy of dipyrone is broad and comparable to that of the non-steroidal anti-inflammatory drugs (NSAIDs) and tramadol. Because dipyrone is a weak cyclo-oxygenase inhibitor, its use is not associated with gastric irritation, an important advantage for long-term administration. Uniquely, dipyrone
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https://doi.org/10.1007/978-981-99-1098-4rofile and incidence of other AEs are not taken into account. An approach to the evaluation of the public health impact of AEs with non-opioid analgesics has now been taken in which the total risk of short-term use of these drugs in the community was estimated. The three dimensional approach involve
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