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Titlebook: Advances in Topical Antifungal Therapy; R. J. Hay Conference proceedings 1986Latest edition Springer-Verlag Berlin Heidelberg 1986 fungi.i

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楼主: patch-test
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Expression of Keratinolytic Activity by ,,imum pH for lysis of guinea pig hair is 7.5. Bifonazole exerts an effect on the in vitro secretion of the protein at the nanogram level, which is far lower than its in vitro MIC level (20 ng/ml as against 0.25–2 µg/ml MIC). Even at 0.6–0.8 ng/ml bifonazole the in vitro lytic activity was reduced to 50% compared with untreated controls.
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Double-Blind Comparative Trial of Three New Antifungal Cream Formulations in Superficial Candidosisological findings, as well as in the final evaluation of the therapeutic value of the drugs..Bifonazole is a drug of proven broad-spectrum antifungal activity. Bearing this in mind, we compared its efficacy and tolerability with those of similar products in the market.
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New Trends in the Treatment of Onychomycosis,e and 40% urea ointment facilitates avulsion of the infected nail, avoiding operative removal of the nail as a rule. In this connection, therapeutic success is not only dependent on the application and efficacy of a preparation, but on the compliance of the patient and his/her efforts to contribute to the success of treatment.
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Preliminary Therapeutic Results in Onychomycosis with a Special Formulation,antifungal might be useful. We propose to use semiocclusion with cellophane or plastic material for the post-treatment with bifonazole cream 1% to achieve better penetration and to enhance the therapeutic activity on the growing nail.
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Investigations into the Anti-inflammatory Effect of Bifonazole,on suggested for this substance is that it inhibits the biosynthesis of ergosterol, which is specifically found in azoles and has a negative effect on the synthesis of the cytoplasmic membrane of fungal cells. In vitro and in vivo tests showed pronounced fungicidal activity against dermatophytes and
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