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Titlebook: Advances in Swine in Biomedical Research; Volume 2 Mike E. Tumbleson,Lawrence B. Schook Book 1996 Springer Science+Business Media New York

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Reproductive Characteristics in Sinclair Miniature Swinewine, were analyzed retrospectively and compared with previously published records representing 1950 to 1952 and 1963 to 1965. Effects of several variables, such as season and month of parturition, age of sow, parity and litter size, on reproductive parameters of Sinclair miniature swine were evalua
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A Comparison of Physiological and Biochemical Parameters in Fully Conscious Hormel-Hanford and Yucatf this strain of miniature pig. The existing strain of miniature pig at our facility was a cross between the Hormel and Hanford strains, bred to be a uniform, compact sized animal with a known pedigree. Because of similarities in the cardiovascular systems of humans and swine, swine often are used i
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The Minipig as a Model for the Study of Aging in Humans concomitant increase in insulin resistance with age. Carbohydrate and lipid metabolism in different metabolic conditions including obesity and noninsulin dependent diabetes mellitus (NIDDM), both of which are age dependent, are controlled by pancreatic, pituitary and adrenal hormones. Therefore, we
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Aging and Miniature Swine Heart and Liver Plasma Membranes 5.9 to 10 yr; and old, 11.5 to 13.9 yr, in male and female Hormel-Hanford miniature swine fed the same energy restricted, low fat, cholesterol free, stock diet continuously post weaning. Mid bilayer heart plasma membrane fluidity, by diphenylhexatriene (DPH) polarization, was increased in old pigs,
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Comparing Porcine Models of Coronary Restenosisocused on the evaluation of novel therapeutic approaches to the treatment of arterial restenosis. It is from this perspective that the following discussion was prepared. Thus, the purpose of this brief review is to present a rationale for the use of the pig, describe the general technique, compare a
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Sinclair Miniature Swine Melanoma as a Model for Evaluating Novel Lymphography Contrast Agentsr birth in up to 54% of the piglets. These tumors readily metastasize to lymph nodes, lung and liver, yet may regress spontaneously due to immune mechanisms. The genetic predisposition, apparent spontaneous transformation and similar histomorphology to human melanomas endorse this model for investig
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The Yucatan Miniature Pig Model of Ventricular Septal Defectve test matings in an experimental herd indicated that the defect is most likely polygenic in transmission. Clinically the defect may be detected by a characteristic mid or holosystolic murmur auscultated over the lower third to fifth intercostal spaces on either side of the thorax. Subpopulations o
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Pregnant Yucatan Miniature Swine as a Model for Investigating Fetal Drug Therapydated as a result of the thalidomide tragedy in the early 1960s. Maternal thalidomide use in the first trimester of pregnancy resulted in approximately 7,000 limb anomalies, with or without gastrointestinal or cardiac malformations.. As a result of this disaster, research was focused on toxicologic
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