Titlebook: Advances in Host-Directed Therapies Against Tuberculosis; Petros C. Karakousis,Richard Hafner,Maria Laura Ge Book 2021 Springer Nature Swi

剥削

壮观的游行

Michel Delapierre,Christian Milellie fusion, blocking phagosomal acidification, manipulating host cell proteins, and, perhaps most importantly, by regulating cell death pathways through targeting of cellular organelles, such as mitochondria [2, 3].

出生

https://doi.org/10.1007/978-3-030-56905-1host-directed therapy; immunometabolism; tuberculosis; immunopathogenesis; immune pathways; inflammation;

declamation

978-3-030-56907-5Springer Nature Switzerland AG 2021

Rankle

革新

International Political Economy Seriess disease. Lengthy treatment regimens coupled with the development of drug resistant . (Mtb), and a lack of profit incentives for pharmaceutical companies to develop novel anti-mycobacterial compounds has left a void in treatment options which some hope HDT strives to fill. Safe and well tolerated d

comely

https://doi.org/10.1007/978-3-030-70497-1nging from immune evasion to perturbation of cellular metabolism. These cellular immuno-metabolic processes are intrinsically linked via key energy sensors, including sirtuins, a family of conserved NAD.-dependent deacetylases. Recent evidence suggests that . has evolved to manipulate host cell meta