Titlebook: Advances in Host-Directed Therapies Against Tuberculosis; Petros C. Karakousis,Richard Hafner,Maria Laura Ge Book 2021 Springer Nature Swi

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https://doi.org/10.1007/978-3-030-70497-1amycin-insensitive companion of mTOR (Rictor), a protein that may have analogous function to Raptor. Among the most recent reviews on the structure and function of the two complexes, the reader is referred to [1]. The primary functions of mTORC1 and mTORC2 are distinct: mTORC1 controls cell growth,

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Michel Delapierre,Christian Milelliegulators etc. At the same time, role of diverse bacterial virulence factors in altering the host autophagy responses has also emerged. In this chapter, we discuss the interplay of host and Mtb, spotlighting the major factors involved in autophagy-dependent targeting of the pathogen and explore the

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India: Fifty years after Independenceh the AMPK-mTORC1-TFEB-autophagy axis. Animal model studies have supported a role for statin adjunctive therapy against TB. Thus, the addition of simvastatin to the first-line antitubercular regimen reduced the duration of curative treatment by one month in the standard mouse model of chronic tuberc

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Targeting Inhibitory Cells Such as Tregs and MDSCs in the Tuberculous Granuloma978-3-642-97923-1

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Type I Interferon and Interleukin-1 Driven Inflammatory Pathways as Targets for HDT in Tuberculosis978-1-4614-0662-4

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Advances in Host-Directed Therapies Against Tuberculosis

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Advances in Host-Directed Therapies Against Tuberculosis978-3-030-56905-1