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Titlebook: Adenosine, Cardioprotection and Its Clinical Application; Robert M. Mentzer,Masafumi Kitakaze,Masatsugu Hori Book 1997 Kluwer Academic Pub

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https://doi.org/10.1007/b137967ong been recognized,. and its vasodilator effects have been proposed as a central mechanism of autoregulation of coronary blood flow.. In addition, its negative inotropic and chronotropic effects have been understood for many years.. However, it has not been until the last decade that adenosine has
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Zahldarstellungen und Stellenwertsysteme,subsequent longer ischemic insult. Preconditioning was originally described a decade ago as a protective intervention that reduced the area of necrosis from a standardized ischemic insult.. Subsequently numerous studies have shown that preconditioning can also provide protection against other detrim
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Grundlagen und Voraussetzungen,ise mechanisms underlying this phenomenon have been investigated. because identification of the primary mediator of ischemic preconditioning may contribute to the development of the potential treatment of acute myocardial infarction. Several lines of evidence suggest that beneficial effects of ische
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https://doi.org/10.1007/b137967likrein-kinin system and plasma aminopeptidase (Fig. 11-1). There are at least two classes of bradykinin receptors, i.e. Bl and B2 receptors, and bradykinin exerts its action on most of the cardiovascular system through B2 receptors. Although bradykinin production in ischemic myocardium was first re
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Lineare und quadratische Kongruenzen,nsult, a phenomenon which has been shown to protect it against infarction, reperfusion arrhythmias, contractile dysfunction and contracture.. This endogenous protective mechanism has been termed ischemic preconditioning,. and appears to occur in all animal species studied,. including man.. The prote
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Zahldarstellungen und Stellenwertsysteme,coronary and systemic vasodilation,. renal vasoconstriction,. slowing of atrial-ventricular (AV) conduction, . inhibition of norepinephrine release from sympathetic nerves,. and inhibition of platelet aggregation.. These properties provide the basis for the current use of adenosine in the clinical a
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