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Titlebook: Acute Leukemias IV; Prognostic Factors a T. Büchner,W. Hiddemann,J. Ritter Conference proceedings 1994 Springer-Verlag Berlin Heidelberg 19

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Die internationale Währungsordnungwhich were destined to change this dismal outlook. The first was the demonstration by Farber et al. [1] that a remission could be induced in children with acute lymphoblastic leukemia (ALL) by the use of an anti-folic antimetabolite. The second was the demonstration by Jacobson et al. [2] that mice
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Martina Zemp,Guy Bodenmann,Peter Zimmermann after ethidium bromide staining [1] and even can be analyzed by sequence analysis. Thus gene sequences altered by rearrangement or translocation typical for certain clonal expansions such as the bcr/abl translocation in chronic myeloic leukemia (CML) (t9; 22) [2,3,4] or the bcl2 rearrangement in fo
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Christina Meurer,Christian Katzenmeierin structural chromosome aberrations in interphase nuclei [2,3]. Numerical chromosome anomalies are determined by enumerating the hybridization signals of specific repetitive α-satellite DNA probes. Thus, FISH which is also referred to as “interphase cytogenetics” extends the possibilities to evalua
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https://doi.org/10.1007/978-3-540-69216-4only few disorders where mono- or oligoclonality is of benign origin and is not associated with malignancy. The detection of a clonal lymphocytic population is thus of great diagnostic interest. Traditionally, the molecular detection of clonal populations is performed by Southern blot analysis of re
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