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Titlebook: Activating and Inhibitory Immunoglobulin-like Receptors; Max D. Cooper,Toshiyuki Takai,Jeffrey V. Ravetch Conference proceedings 2001 Spri

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Australia in the Expanding Global Crisisate ‘costimulatory’ and inhibitory signals in T cells, respectively. The crystal structure of the extracellular region of B7-1 (sB7-l), solved to 3 Å resolution, consists of a novel combination of two Ig-like domains, one characteristic of adhesion molecules and the other previously seen only in ant
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https://doi.org/10.1007/978-3-319-76911-0VI binds to exposed collagen fibres at the site of vascular damage and the ensuing signalling events contribute to formation of a thrombus to repair the damaged area. The control of this activatory signalling pathway by immunoreceptor tyrosine-based inhibitory motif (ITIM) containing molecules is be
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https://doi.org/10.1007/978-3-319-76911-0eceptor families, so-called activating receptors and inhibitory receptors. With the aim of identifying novel NK receptors, we generated mAbs by immunizing activated NK cells and selected a novel mAb designated Yuri3. Biochemical and molecular analysis indicated that Yuri3 recognizes mouse CD94. Here
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https://doi.org/10.1007/978-3-319-76911-0 immunoreceptors. The HCMV-encoded MHC class I homolog, UL18, binds to LIR-1/ILT2, an inhibitory signaling receptor for cellular MHC class I antigens with a broad distribution on leukocytes, including some NK cells. Although UL18 has been proposed to act as an inhibitor of NK cytotoxicity, this rema
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The Children’s Court of Victoriaassociates with BCR and is phosphorylated upon BCR ligation, resulting in recruitment of the SHP-1 phosphatase. CD72-deficient B cells show enhanced ERK activation and calcium mobilization upon BCR ligation, indicating that CD72 negatively regulates BCR signaling probably by activating SHP-1, thereb
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