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Titlebook: Voltammetry in the Neurosciences; Principles, Methods, Joseph B. Justice Book 1987 Springer Science+Business Media New York 1987 brain.cate

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发表于 2025-3-21 17:29:11 | 显示全部楼层 |阅读模式
书目名称Voltammetry in the Neurosciences
副标题Principles, Methods,
编辑Joseph B. Justice
视频video
丛书名称Contemporary Neuroscience
图书封面Titlebook: Voltammetry in the Neurosciences; Principles, Methods, Joseph B. Justice Book 1987 Springer Science+Business Media New York 1987 brain.cate
描述Even before the time of organized scientific investigation, hu­ mans had begun pondering and attempting to explain the work­ ing of the brain and the mental and behavioral states it produces. In the last twenty years there has been an almost explosive in­ crease in brain research. Beginning perhaps with the pioneering efforts of Francis O. Schmitt to establish the Neuroscience Re­ search Program and the later development of the Society for Neuroscience, there has emerged a large and powerful multi­ disciplinary research force devoted to understanding even the ru­ dimentary aspects of brain functioning. Chemists, physicists, and engineers with their special expert­ ise in quantitative physical measurements have teamed up with the neurobiologists, who best know the texture and design of brains, to produce particularly effective new approaches. No­ where is this more evident than in the recently developed meth­ ods like positron emission tomography and magnetic resonance imaging-techniques that allow one to observe on-going brain ac­ tivity in humans. This volume concerns a considerably more modest approach: the use of microelectrodes to electrochemically monitor certain aspects of ch
出版日期Book 1987
关键词brain; catecholamines; dopamine; magnetic resonance imaging (MRI); neurochemistry; neurons; neuroscience; p
版次1
doihttps://doi.org/10.1007/978-1-59259-463-4
isbn_softcover978-1-4757-6951-7
isbn_ebook978-1-59259-463-4
copyrightSpringer Science+Business Media New York 1987
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Introduction to In Vivo Voltammetryular, the easily oxidizable catecholamine and indoleamine neurotransmitters, metabolites, and related compounds can be studied with this technique. Since the original report from the laboratory of R. N. Adams (Kissinger et al., 1973), more than 150 papers have been published on in vivo voltammetry a
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Quantitative Interpretations of In Vivo Chronoamperometry5-HT), as well as ascorbic and uric acid. There are many different groups working on various aspects of the function of these substances (. Adams and Marsden, 1979; and Marsden, 1984). To date the electrochemical signals that have been measured have largely been interpreted only as evidence for a st
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In Vivo Electrochemical Monitoring of Dopamine Releasen et al., 1984). Moreover, at least nine chapters of this volume will be entirely or partly devoted to this subject. Therefore this problem does not require further introduction. For the same reason the present chapter may not be an objective review on this subject since I plan to concentrate on our
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Monitoring Extracellular DOPAC Following Stimulated Release of Dopamineimals are needed to complement studies using lesions of dopaminergic systems. Monitoring DA release directly is relatively difficult, particularly in behaving animals. One approach to the problem of monitoring DA release has been to use metabolite levels, either total tissue levels or extracellular
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In Vivo Voltammetryincipally ligand binding methods. It is essential, however, that a correlation is demonstrated between the ligand binding data and a functional response. The latter should preferably be in vivo, such as a behavioral or physiological response. This can prove difficult especially with regard to recept
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