Titlebook: Voltammetric Methods in Brain Systems; Alan A. Boulton,Glen B. Baker,Ralph N. Adams Book 1995 Humana Press 1995

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Monitoring Dopamine and Noradrenaline Release in Central and Peripheral Nervous Systems with Treatemmetric peak that was entirely owing to extracellular DA providing that rats were treated with an inhibitor of monoamine oxidase, pargyline (Gonon et al., 1984a). The fact that 10 yr of intense efforts were required to obtain the first reliable measurements points out how difficult the task was.

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Fast Cyclic Voltammetry in Brain Slices,onal studies have drawbacks. First, it is often necessary to label the neurotransmitter pool with tritium (Farnebo and Hamberger, 1971). This assumes, probably fallaciously, that release of the radiolabel accurately reflects the neurotransmitter. For example, when endogenous and radiolabeled catecho

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Monitoring Dopamine and Noradrenaline Release in Central and Peripheral Nervous Systems with Treatee performed by Adams and coworkers in 1973 (Kissinger et al., 1973). However, the unequivocal monitoring of DA released by dopaminergic terminals in the rat striatum was accurately achieved only 10 yr after. In 1983, Wightman and coworkers were able to record with fast cyclic voltammetry the DA rele

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Regional Differences in Dopamine Release, Uptake, and Diffusion Measured by Fast-Scan Cyclic Voltamimbic regions. Appropriate control of its role in communication between neurons is clearly important for normal function. Possibly the most recognizable aspect of improper regulation of DA is Parkinson’s disease. The symptoms of this neurodegenerative disorder, which affects the control of motor act

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The Measurement of Brain Ascorbate In Vivo and Its Link with Excitatory Amino Acid Neurotransmissiorotecting tissues from harmful free radicals and maintaining certain enzymes in their reduced form (Padh, 1990). Although mechanisms of its roles are often unknown or only poorly understood, details of specific interactions of AA with a variety of molecular complexes, such as calcium channels (Parse

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Voltammetric and Amperometric Probes for Single-Cell Analysis,ics of single nerve cells should lead to better models of the cellular neurotransmission process. Information of this type promises to advance our knowledge of neurotransmitter storage, exocytosis, and the physiological effects of external stimuli, such as drugs and toxins. Advances in these areas r

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Measurement of the Time-Resolved Kinetics of Biogenic Amine Release and Transporter Activity by Rotnervous systems. Studies of this process are made by a variety of approaches and from different research perspectives, such as those of the molecular, genetic, molecular biological, cellular, and behavioral sciences. Chemical neurotransmission and its effects are transient events that in some cases