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Titlebook: Vitamin D Analogs in Cancer Prevention and Therapy; Jörg Reichrath,Wolfgang Tilgen,Michael Friedrich Conference proceedings 2003 Springer-

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Mechanisms Implicated in the Growth Regulatory Effects of Vitamin D Compounds in Breast Cancer Cells and differentiation in many cell types, including breast cancer. However, any potential anti-tumour properties displayed by 1,25(OH).D. are limited by the tendency to cause hypercalcaemia when administered at high doses. Because of this, synthetic vitamin D analogues have been developed that retain
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Cultured Rat Growth Plate Chondrocytes Express Low Levels of 1α-Hydroxylasethese polar metabolites were inconclusive in various in vitro systems, the expression of a potential paracrine/autocrine vitamin D system was examined in primary cultures of rat growth plate chondrocytes using real-time RT-PCR. Compared to UMR cells and renal homogenates primary cultures of growth p
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Regulation of the 25-Hydroxyvitamin D-1α-Hydroxylase Gene and Its Splice Variants expressed in kidneys, but also is expressed in many nonrenal tissues, including skin. In this study, we compared the regulation of the 1α-OHase expression in kidney cells and keratinocytes. Using transfected luciferase reporter gene constructs, we compared the activity and regulatory features of t
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