Titlebook: Viruses and Human Cancer; From Basic Science t Mei Hwei Chang,Kuan-Teh Jeang Book 20141st edition Springer-Verlag Berlin Heidelberg 2014 Ca

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Virus Infection and Human Cancer: An Overview,developing world. Oncogenic viruses include various classes of DNA and RNA viruses and induce cancer by a variety of mechanisms. A unifying theme is that cancer develops in a minority of infected individuals and only after chronic infection of many years duration. The viruses associated with the gre

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The Oncogenic Role of Hepatitis B Virus,million chronically infected people at increased risk of developing liver disease and hepatocellular carcinoma (HCC). HBV has been classified among human tumor viruses by virtue of a robust epidemiologic association between chronic HBV carriage and HCC occurrence. In the absence of cytopathic effect

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Prevention of Hepatitis B Virus Infection and Liver Cancer,of HCC in the world, particularly in areas prevalent for HBV infection such as Asia, Africa, southern part of Eastern and Central Europe, and the Middle East. Risk factors of HBV-related HCC include (1) viral factors—persistent high viral replication, HBV genotype C or D, pre-S2 or core promoter mut

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The Oncogenic Role of Hepatitis C Virus,ial in the pathogenesis of HCC associated with HCV whether the virus plays a direct or an indirect role. The observation that chronic hepatitis C patients with sustained high levels of serum alanine aminotransferase are prone to develop HCC suggests the significance of inflammation in hepatocarcinog

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Prevention of Hepatitis C Virus Infection and Liver Cancer,. The majority of HCC cases are associated with chronic viral hepatitis. With over 170 million individuals chronically infected with hepatitis C virus (HCV) worldwide, HCV is currently a serious global health concern, leading to chronic hepatitis, cirrhosis and HCC, thereby causing significant morbi

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The Role of Human Papillomaviruses in Oncogenesis,y induced cancers in the USA are associated with HPV infections. HPVs infect stratified epithelia and link productive replication with differentiation. The viral oncoproteins, E6, E7, and E5, play important roles in regulating viral functions during the viral life cycle and also contribute to the de

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Control of HPV Infection and Related Cancer Through Vaccination,ity in over 600 million infected individuals. Major progress has been made with preventative vaccines, and clinical data have emerged regarding the efficacy and cross-reactivity of the two FDA approved L1 virus like particle (VLP)-based vaccines. However, the cost of the approved vaccines currently

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,Prevention and Treatment for Epstein–Barr Virus Infection and Related Cancers,ferative diseases (PTLD) and several other cancers in non-immunocompromised patients, with more than 200,000 new cases per year. While prevention of PTLD is improving, mainly based on EBV monitoring and preemptive tapering of immunosuppression, early diagnosis remains the best current option for the