| 书目名称 | Virus Host Cell Genetic Material Transport | | 副标题 | Computational ODE/PD | | 编辑 | William E. Schiesser | | 视频video | http://file.papertrans.cn/984/983508/983508.mp4 | | 概述 | Provides a detailed discussion on the reproduction and spread of a virus during an epidemic.Presents research findings through detailed examples, rather than formal mathematics, so that the reader can | | 图书封面 |  | | 描述 | .The reproduction and spread of a virus during an epidemic proceeds when the virus attaches to a host cell and viral genetic material (VGM) (protein, DNA, RNA) enters the cell, then replicates, and perhaps mutates, in the cell. The movement of the VGM across the host cell outer membrane and within the host cell is a spatiotemporal dynamic process that is modeled in this book as a system of ordinary and partial differential equations (ODE/PDEs). .The movement of the virus proteins through the cell membrane is modeled as a diffusion process expressed by the diffusion PDE (Fick’s second law). Within the cell, the time variation of the VGM is modeled as ODEs. The evolution of the dependent variables is computed by the numerical integration of the ODE/PDEs starting from zero initial conditions (ICs). The departure of the dependent variables from zero is in response to the virus protein concentration at the outer membrane surface (the point at which the virus binds to the host cell). .The numerical integration of the ODE/PDEs is performed with routines coded (programmed) in R, a quality, open-source scientific computing system that is readily available from the Internet. Formal mathematics | | 出版日期 | Book 2022 | | 关键词 | virus protein; ODE/PDE model; R routines; ODE/MOL routine; Host Cell Proteins; Postulated vaccine; Postula | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-030-68865-3 | | isbn_softcover | 978-3-030-68867-7 | | isbn_ebook | 978-3-030-68865-3 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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