书目名称 | Viral Vectors for Gene Therapy | 副标题 | Methods and Protocol | 编辑 | Fredric P. Manfredsson,Matthew J. Benskey | 视频video | | 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | This volume discusses protocols, ranging from vector production to delivery methods, used to execute gene therapy applications. Chapters are divided into four parts, and cover topics such as design, construction, and application of transcription activation-like effectors; multi-modal production of adeno-associated virus; construction of oncolytic herpes simplex virus; AAV-mediated gene delivery to the mouse liver; and intrathecal delivery of gene therapeutics by direct lumbar puncture in mice. Written in the highly successful .Methods in Molecular Biology. series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..Comprehensive and authoritative, .Viral Vectors for Gene Therapy: Methods and Protocols. is a valuable resource for researchers, clinicians, and students looking to utilize viral vectors in gene therapy experiments.. | 出版日期 | Book 2019 | 关键词 | Recombinant viral vectors; Gene expression manipulation; Genetic modification; Vector delivery; Pharmaco | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4939-9065-8 | isbn_ebook | 978-1-4939-9065-8Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media, LLC, part of Springer Nature 2019 |
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