Titlebook: Viral Membrane Proteins: Structure, Function, and Drug Design; Wolfgang B. Fischer Book 2005 Springer-Verlag US 2005 HIV.biochemistry.enzy

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Diversity of Coronavirus Spikes: Relationship to Pathogen Entry and Disseminationcluding bronchitis, gastroenteritis, hepatitis, and encephalitis, with symptoms ranging from being nearly undetectable to rapidly fatal. A combination of interacting variables determine the pattern and severity of coronavirus-induced disease, including the infecting virus strain, its transmission st

thwart

Aspects of the Fusogenic Activity of Influenza Hemagglutinin Peptides by Molecular Dynamics Simulati studied by molecular dynamics (MD) simulations. This domain is considered a model system for studying processes occurring during viral membrane fusion. Synthetic peptides corresponding to this domain are able to cause red blood cell hemolysis and leakage of liposomal content. Mutations in their seq

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SPALL

Influenza A Virus M2 Protein: Proton Selectivity of the Ion Channel, Cytotoxicity, and a Hypothesis proton channel activity is essential for virus uncoating and in certain cases for the maturation of viral hemagglutinin (HA). A fluorimetric assay of ion translocation by membrane-reconstituted M2 disclosed the nature of the conducted ions, protons, and allowed the determination of an average unita

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Regurgitation

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Defining Drug Interactions with the Viral Membrane Protein Vpu from HIV-1CD4, the HIV-1 receptor, and (b) by amplifying particle release at the site of the plasma membrane. While the first role is due to interactions of the cytoplasmic site of Vpu with CD4, the second role may be due to ion channel activity caused by the self-assembly of the protein. Recently, a blocker

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Book 2005mbrane proteins encoded by viruses. In addition, contributors to the book address questions about proteins as potential drug targets. The range of information covered includes signal proteins, ion channels, and fusion proteins...This book has a place in the libraries of researchers and scientists in

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as a place in the libraries of researchers and scientists in a wide array of fields, including protein chemistry, molecular biophysics, pharmaceutical science and research, bioanotechnology, molecular biology, and biochemistry..978-1-4419-3453-6978-0-387-28146-9