Titlebook: Vascular Mechanisms in CNS Trauma; Eng H. Lo,Josephine Lok,Michael J. Whalen Book 2014 Springer Science+Business Media New York 2014 blood

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Human Cerebral Blood Flow and Traumatic Brain Injuryt diffusible gas (nitrous oxide), measuring it in arterial and jugular venous blood, and applying the Fick principle of blood flow determination they were able to calculate a global rate of CBF of mL/100 g/min. Kety–Schmidt-based CBF measurements evolved over the next 2 decades by the substitution o

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Angiogenesis and Functional Recovery After Traumatic Brain Injuryever, nearly all Phase III traumatic brain injury (TBI) clinical trials have failed to provide safe and effective treatment for improving functional recovery after TBI. This review discusses recent promising preclinical and clinical data indicating that TBI promotes angiogenesis (formation of new bl

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Vascular Mechanisms in Spinal Cord Injury Major breakthroughs have been made by using endothelial cell-selective treatments to show that endothelial cell survival and function is key to protecting the spinal cord tissue. Other vascular treatment strategies involve the reduction of detrimental leakage and improving microvascular perfusion a

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Vascular Actions of Hypothermia in Brain Trauma no approved therapies to treat the devastating consequences of severe TBI. Therapeutic hypothermia has a history of showing efficacy both in animal models and clinical studies. Potential mechanisms by which hypothermia may improve traumatic outcome include targeting vascular alterations such as by

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