Titlebook: Vanadium Compounds: Biochemical and Therapeutic Applications; Ashok K. Srivastava,Jean-Louis Chiasson Book 1995 Kluwer Academic Publishers

Vasoconstrictor

确定的事

猜忌

老人病学

Vanadium chemistry and biochemistry of relevance for use of vanadium compounds as antidiabetic agenttly used as insulin-mimetic agents in animal and human studies are stable upon dissolution in distilled water but lack such stability in distilled water at pH 7. Complex lability may result in decomposition at neutral pH and thus may compromise the effectiveness of these compounds as therapeutic age

Corral

Peroxo heteroligand vanadates(V): Synthesis, spectra-structure relationships, and stability toward daracterized by analysis, IR, UV/V and NMR spectra. X-ray structures for some were obtained. The vanadates(V) contain the cation M(I) = Na, K, NH., Rb or Cs. Diperoxo complexes include M(I)[VO(O.). L], where L = dipyridyl, o-phenanthroline; M(I).[VO(O.).(C.O.)]; K.[(nicotinic acid){VO(O.).}.]H.O;M(I)

mighty

misshapen

Insulin-like actions of vanadate are mediated in an insulin-receptor-independent manner via non-receV) form. Although this element is essential and should be present in the diet in minute quantities, no known physiological role for vanadium has been found thus far. In the years 1975—1980 the vanadate ion was shown to act as an efficient inhibitor of Na.,K.-ATPase and of other related phosphohydrol

ascend

混乱生活

旋转一周

Vanadium salts stimulate mitogen-activated protein (MAP) kinases and ribosomal S6 kinasesnine kinases in Chinese hamster ovary (CHO) cells overexpressing a normal human insulin receptor was examined. All the compounds stimulated protein tyrosine phosphorylation of two major proteins with molecular masses of 42 kDa (p42) and 44 kDa (p44). The phosphorylation of p42 and p44 was associated