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Titlebook: Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk; Frederick J. Serres,William Sheridan

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书目名称Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk
编辑Frederick J. Serres,William Sheridan
视频videohttp://file.papertrans.cn/945/944697/944697.mp4
丛书名称Environmental Science Research
图书封面Titlebook: Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk;  Frederick J. Serres,William Sheridan
描述The magnitude of the threat to the human genetic material posed by environmental agents has not as yet been fully determined. Never­ theless, the potential hazards of many chemicals have been identi­ fied by studies on lower organisms. However, too little is known regarding the comparability or lack of it between the metabolic pathways available in such organisms and those in man. Although at present there is great public concern for what is considered by some as the excessive use of laboratory animals in toxicological testing, it seems clear that the usage of mammalian systems may be deemed necessary. It has been proposed that cell culture systems might suffice to meet this need, however, such approaches cannot match the complexity of physiological occurances that are present in the intact animal. For studies of genetic effects, some non-invasive human test systems are presently available. These do not, however, meet the re­ quirements for extensive laboratory studies. In order to assess the risks to humans of environmental factors such laboratory investiga­ tions are essential. Therefore, for the forseeable future reliance on experiments using laboratory animals will be necessary
出版日期Book 1983
关键词Potential; complexity; environment; environmental health; experiment; health; risk assessment
版次1
doihttps://doi.org/10.1007/978-1-4613-3739-3
isbn_softcover978-1-4613-3741-6
isbn_ebook978-1-4613-3739-3
copyrightPlenum Press, New York 1983
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https://doi.org/10.1007/978-1-4613-3739-3Potential; complexity; environment; environmental health; experiment; health; risk assessment
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Book 1983ntial hazards of many chemicals have been identi­ fied by studies on lower organisms. However, too little is known regarding the comparability or lack of it between the metabolic pathways available in such organisms and those in man. Although at present there is great public concern for what is cons
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ly available. These do not, however, meet the re­ quirements for extensive laboratory studies. In order to assess the risks to humans of environmental factors such laboratory investiga­ tions are essential. Therefore, for the forseeable future reliance on experiments using laboratory animals will be necessary978-1-4613-3741-6978-1-4613-3739-3
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Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk
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Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk978-1-4613-3739-3
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iate levels of military force. Seeking to avoid undue reliance on nuclear weapons, and so enhance the credibility of its deterrent, NATO favoured responding to a conventional attack in kind. Committed to a forward defence of NATO territory, it would hope to hold any attack with conventional forces,
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