Titlebook: Urticaria and Angioedema; Torsten Zuberbier,Clive Grattan,Marcus Maurer Book 2021Latest edition Springer Nature Switzerland AG 2021 Dermat

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Aetiopathogenesis of Urticaria,sies of chronic spontaneous urticaria include T cells, eosinophils, basophils and neutrophils. The role of these cells and their interactions is not yet clear during wheal development and resolution. Th0 cells predominate in chronic urticaria, Th2 initiating cytokines are found in lesional skin. Inc

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Classification and Diagnosis of Urticaria,xist in any given patient. Subtypes of urticaria display diverse but common histological features as seen in a wide variety of inflammatory reactions, and therefore have no diagnostic value. The current guidelines recommend a simple classification based on clinical symptoms, their duration, and if t

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Impact of Chronic Urticaria and How to Measure It,ients never know when, where and how strong their signs and symptoms will occur. Accordingly, CSU has a major physical, emotional, and social impact on the patients’ lifes and is frequently associated with an impairment of daily life activities, sleep deprivation, and psychiatric comorbidities. In a

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Acute Urticaria,nt hives only which helps to differentiate from other diseases where whealing may occur..While the lifetime prevalence has been reported to be high, spontaneous resolve has been seen in the majority of patients in the first 3 weeks after onset..Multiple triggers have been described, beside viral inf

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Chronic Spontaneous Urticaria,superficial skin swellings of variable size that are associated with itching or burning (Fig. 6.1). Weals come with flare reactions of the surrounding skin, and they resolve spontaneously (usually within several hours). Angio-oedemas are sudden, deeper, pronounced, and sometimes painful swellings of

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Chronic Spontaneous Urticaria and Comorbidities,orbidities, e.g., autoimmune diseases, are more common in CSU patients, and CSU patients may benefit from screening for these conditions. Other CSU comorbidities such as metabolic syndrome are under-recognized in CSU. As of yet, urticaria guidelines do not provide specific diagnostic recommendations

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