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Titlebook: Unexplained Infertility; Pathophysiology, Eva Glenn L. Schattman,Sandro C. Esteves,Ashok Agarwal Book 2015 Springer Science+Business Media,

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Genetic Basis of Unexplained Male Infertilityation regardless of semen analyses results, are classified as having infertility of unknown origin. In several of these cases, etiologies may be is gene related including chromosomal defects, gene mutations, DNA damage, sperm chromosomal abnormalities, and epigenetic disorders. In this chapter, we r
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Role of the Immune System in Unexplained Male Infertility develop during later stages of spermatogenesis. These “nonself” antigens are sequestered from the immune attack by the blood–testis barrier. The most frequent phenomenon of immune pathology in infertility is the development of antibodies directed to these “nonself” antigens that are relevant to spe
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Oxidative Stress in Unexplained Male Infertilityd idiopathic infertility, the components of an infertility workup, and the parameters addressed in a routine semen analysis necessary to diagnose unexplained infertility. Furthermore, it elaborates upon the various etiologies suggested to play a role in UMI, such as coital problems, physical aberrat
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Role of Environmental Factors and Gonadotoxin Exposure in Unexplained Male Infertilityy (UMI). Researchers believe that the ever-changing environmental and lifestyle conditions to which the human body is exposed throughout an entire lifespan contribute greatly to this deterioration. Developments in industry and changes in modern lifestyle give rise to a range of different factors suc
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