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Titlebook: Uncertainty in Pharmacology; Epistemology, Method Adam LaCaze,Barbara Osimani Book 2020 Springer Nature Switzerland AG 2020 Drug Developmen

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A Millian Look at the Logic of Clinical Trials and, more generally, hypotheses of statistical causality, are provided by an appropriate statistical version of such a venerable procedure as the method of difference put forward by John Stuart Mill.
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Epistemic Gains and Epistemic Games: Reliability and Higher Order Evidence in Medicine and Pharmacold for defeasibility of causal inference in such domains. I then present a system for probabilistic causal assessment from heterogenous evidence that makes justice of concerns from both positions, while also incorporating “higher order evidence” (evidence/information about the evidence itself) in hypothesis confirmation.
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In Silico Clinical Trials: A Possible Response to Complexity in Pharmacology doing research, thought to be more adequate to address biological complexity. In this chapter we analyze such a view by showing how these new computational strategies enhance and implement traditional approaches rather than changing the nature of clinical investigation. An epistemic look at ISCTs s
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