| 书目名称 | Tumor Microenvironment | | 副标题 | The Main Driver of M | | 编辑 | Jacinta Serpa | | 视频video | | | 概述 | An integrative view of tumor microenvironment and cancer metabolic adaptations, focusing different cancer contexts and interspecific cellular actions.A wide range of traits, showing the way cancer ada | | 丛书名称 | Advances in Experimental Medicine and Biology | | 图书封面 |  | | 描述 | The way a cell undergoes malignant transformation should meet their capacity of surviving in the microenvironment of the organ where the cancer will develop. Metabolic adaptation is for sure one of the criteria that must be accomplished, driven by metabolic plasticity that allows the adaptation of cancer cells to the availability of energy and biomass sources that will sustain cell survival and proliferation. Each human organ has a particular microenvironment which depends on several cell types and in some cases also on symbiotic microorganisms. These biological partners are constantly sharing organic compounds and signaling molecules that will control mitogenesis, cell death and differentiation, accounting for the organ‘s function. Nevertheless, cancer cells are capable of taking advantage of this metabolic and signaling microenvironmental dynamics..In this book, we intend to present the different components of the microenvironment driving the metabolic fitness of cancer cells. Themetabolic changes required for establishing a tumor in a given microenvironment and how these metabolic changes limit the response to drugs will generally be the major items addressed. It is important to | | 出版日期 | Book 2020 | | 关键词 | cancer metabolism; cell survival; intercellular cooperation; metabolic signaling; metabolomics | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-030-34025-4 | | isbn_softcover | 978-3-030-34027-8 | | isbn_ebook | 978-3-030-34025-4Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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发表于 2025-3-21 19:31:17
