| 书目名称 | Tumor Microenvironment |
| 编辑 | Peter P. Lee,Francesco M. Marincola |
| 视频video | |
| 概述 | Discusses numerous aspects of immune landscapes and their biology.Explores the relation between the tumor microenvironment and therapy.Examines advances in imaging of the tumor microenvironment |
| 丛书名称 | Cancer Treatment and Research |
| 图书封面 |  |
| 描述 | .This book addresses the biological processes relevant to the immune phenotypes of cancer and their significance for immune responsiveness, based on the premise that malignant cells manipulate their surroundings through an evolutionary process that is controlled by interactions with innate immune sensors as well as the adaptive recognition of self/non-self. Checkpoint inhibitor therapy is now an accepted new form of cancer treatment. Other immuno-oncology approaches, such as adoptive cell therapy and metabolic inhibitors, have also shown promising results for specific indications. Immune resistance is common, however, limiting the efficacy of immunotherapy in many common cancer types. .The reasons for such resistance are diverse and peculiar to the immune landscapes of individual cancers, and to the treatment modality used. Accordingly, approaches to circumvent resistance need to take into account context-specific genetic, biological and environmental factors that may affect the cancer immune cycle, and which can best be understood by studying the target tissue and correlated systemic immune markers. .Understanding the major requirements for the evolutionary process governing human |
| 出版日期 | Book 2020 |
| 关键词 | Tumor Microenvironment; Spatial Imaging; Immune Landscapes; Adaptive Immunity; Hypoxia; CAR T cell therap |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-030-38862-1 |
| isbn_softcover | 978-3-030-38864-5 |
| isbn_ebook | 978-3-030-38862-1Series ISSN 0927-3042 Series E-ISSN 2509-8497 |
| issn_series | 0927-3042 |
| copyright | Springer Nature Switzerland AG 2020 |
发表于 2025-3-21 19:54:42
