书目名称 | Tumor Ecosystem | 副标题 | An Ecological View o | 编辑 | Erwei Song | 视频video | | 概述 | Propose a new concept of onco-spheres in cancer ecosystem.Delve into the interactions of various cells, different organs, host and guests in onco-spheres.Written by experts in tumor research field | 图书封面 |  | 描述 | .This book intends to report new concept of .onco-spheres. .in cancer ecosystem. .Onco-spheres. are defined as where cancer cells (living organisms) dynamically interact with nontumor cellular (other living organisms) and noncellular components (non-living environmental factors) in the ‘host’ internal environment (habitat) to construct a self-sustainable cancer ecosystem, which can be scoped at three different levels: primary/regional, distal and systemic .onco-spheres....Cancer cells should be conceived as ‘living organisms’, interacting with cellular or noncellular components in the host internal environment, not only with the local tumor microenvironment (TME) but also constantly communicating with a distant organ niche as well interacting with the host’s nervous, endocrine and immune systems, to construct a self-sustainable ‘biosphere’, as we termed the .tumor ecosystem.. By looking at theinteraction of cancer and host as a unique ecosystem, we will use ecology principles to further delineate the features of the dynamics of the tumor ecosystem. ..As the pioneer in proposing this concept, we feel that this full-scale overview of the tumor ecosystem is able to inform the readers | 出版日期 | Book 2023 | 关键词 | Cancer ecosystem; Local, pre-metastatic and global cancer niche; Immunity, inflammation and cancer; Neu | 版次 | 1 | doi | https://doi.org/10.1007/978-981-99-1183-7 | isbn_softcover | 978-981-99-1185-1 | isbn_ebook | 978-981-99-1183-7 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor |
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